Overview of the 2025 CPT Code Updates
11,321
Total CPT codes in 2025
270
Added codes
112
Deleted codes
38
Revised codes
Key Highlights of the 2025 Updates
The largest share of new codes (37%) are related to Proprietary Laboratory Analyses (PLA), particularly focusing on advanced genetic testing. This emphasizes the growing role of personalized medicine in healthcare.
Major Sections with Updates
- Surgery
- Evaluation and Management (E&M)
- Radiology, Pathology, Laboratory, and Medicine
- Category III Codes
- Proprietary Laboratory Analyses (PLA)
2025 Surgical CPT Codes (10004 - 69990)
The section within the CPT code set on general surgery has been revised to incorporate new surgical approaches and techniques, especially in the areas pertaining to skin grafting and tumor removal in the abdomen.
- Integumentary system (10030-19499): 8 new codes, 2 deleted
- Musculoskeletal system (20100-29999): 1 new code, 1 revised
- Hemic and lymphatic systems (38100-38999): 4 new codes
- Digestive system (40490-49999): 5 new codes, 4 deleted
- Urinary system (50010-53899): 3 new codes, 2 deleted
- Nervous system (61000-64999): 7 new codes
Specialty-Specific Highlights
Cardiology Updates
New Category III codes focus on advancements in electrocardiogram and cardiac contractility modulation-defibrillator systems.
Radiology Updates
New codes include MRI-monitored transurethral ultrasound ablation of the prostate, transcranial Doppler, percutaneous radiofrequency ablation of the thyroid, and MRI safety assessments.
Vaccines and Labs
Changes include vaccination codes, proprietary laboratory analysis, and genetic testing. New genetic counseling code (96041) replaces 96040.
Telemedicine and Remote Patient Monitoring
Remote Patient Monitoring (RPM)
- CPT 98975: Expanded to include digital therapeutic interventions
- CPT 98976–98978: Updated to cover devices enabling data access or transmission for RPM
- CPT 98980: Adjusted to require 11–20 minutes of provider time
- Six new codes address RPM for shorter durations (2-15 days)
Telemedicine Updates
- 17 new codes for audio-video visits: New patients (98000–98003), Established patients (98004–98007)
- Audio-only telemedicine codes: New patients (98008–98011), Established patients (98012–98015)
- New virtual check-in code (98016) replaces HCPCS code G2012
Augmented/Artificial Intelligence (AI) Codes
Seven new Category III codes highlight AI's growing impact in healthcare:
- 0877T–0880T: AI-powered analysis of medical chest imaging
- 0898T: AI-guided prostate biopsies
Preparation for 2025 CPT Updates
To adapt to these changes, providers and billers should:
- Acquire updated CPT manuals
- Update electronic health record (EHR) systems
- Communicate with payers regarding coverage policies
- Train staff on new coding requirements
- Ensure providers are familiar with specialty-relevant updates