How many new ICD-10-CM codes are added in FY 2025?

FY 2025 ICD-10-CM includes 252 new codes, 34 deletions, and 13 code descriptor revisions, effective October 1, 2024.

What are the major chapter updates in FY 2025 ICD-10-CM?

Major updates include Chapter 2 (Neoplasms) with 63 new codes and 'in remission' options, Chapter 5 (Mental and Behavioral) with 26 new eating disorder codes, Chapter 4 (Endocrine) with presymptomatic Type 1 diabetes codes, and Chapter 13 (Musculoskeletal) with 33 new codes for lumbar disc degeneration.

What new diabetes codes are in FY 2025 ICD-10-CM?

FY 2025 introduces E10.A- codes for presymptomatic Type 1 diabetes mellitus, which are assigned for early-stage type 1 diabetes that predates the onset of diabetic symptoms.

When do the FY 2025 ICD-10-CM changes take effect?

The FY 2025 ICD-10-CM code updates are effective October 1, 2024. Healthcare organizations should review code deletions and reclassifications before this date.

FY 2025 ICD-10-CM Code Updates

Codes Summary

252

New codes added

34

Codes deleted

13

Code titles revised

Although fewer in number than previous years, the FY 2025 ICD-10-CM code updates bring significant new classifications effective October 1, 2024.

Code Descriptor Revisions

The FY 2025 ICD-10-CM code updates include 13 code descriptor revisions. Key examples include:

A7741: Changed from "Ehrlichiosis chafeensis [E. chafeensis]" to "Ehrlichiosis chaffeensis [E. chaffeensis]"
F9821: Changed from "Rumination disorder of infancy" to "Rumination disorder of infancy and childhood"
G9342: Changed from "Megaloencephalic leukoencephalopathy with subcortical cysts" to "Megalencephalic leukoencephalopathy with subcortical cysts"
H442A3-H442E3: Degenerative myopia codes revised from "bilateral eye" to "bilateral"
I2693: Changed from "Single subsegmental pulmonary embolism" to "Single subsegmental thrombotic pulmonary embolism"
I2694: Changed from "Multiple subsegmental pulmonary emboli" to "Multiple subsegmental thrombotic pulmonary emboli"
K589: Changed from "Irritable bowel syndrome without diarrhea" to "Irritable bowel syndrome, unspecified"
Q1381: Changed from "Rieger's anomaly" to "Rieger anomaly"
Z6854: Changed from "BMI pediatric, greater than or equal to 95th percentile" to "BMI pediatric, 95th percentile to less than 120% of 95th percentile"

Code Deletions

The FY 2025 ICD-10-CM code updates include 34 code deletions. Notable deletions include:

C8339: Diffuse large B-cell lymphoma, extranodal and solid organ sites
C860-C866: Multiple NK/T-cell lymphoma codes
C880-C889: Immunoproliferative disease codes including Waldenstrom macroglobulinemia
E340: Carcinoid syndrome
E668: Other obesity
F5001-F5002: Anorexia nervosa subtypes
F502: Bulimia nervosa
F5081: Binge eating disorder
K603-K605: Anal, rectal, and anorectal fistula codes
M5136-M5137: Intervertebral disc degeneration, lumbar/lumbosacral region
T8132X series: Disruption of internal operation wound codes

Important: Code deletions indicate that conditions have been reclassified to more specific codes. Review the new code assignments before the October 1, 2024 effective date.

Chapter-by-Chapter Breakdown

Distribution of ICD-10-CM code updates by chapter:

Chapter 2

Neoplasms (C00-D49)

63 new codes, 14 invalidated - Codes in categories C81-C84 now have "in remission" options.

Chapter 5

Mental & Behavioral (F01-F99)

26 new codes, 1 revision, 4 invalidated - Eating disorder codes expanded for severity.

Chapter 4

Endocrine & Metabolic (E00-E89)

16 new codes - Including presymptomatic Type 1 diabetes (E10.A-), hypoglycemia level (E16.A-), and obesity class (E66.8).

Chapter 13

Musculoskeletal (M00-M99)

33 new codes, 3 invalidated - Lumbar disc degeneration codes expanded to specify pain type.

Additional Chapter Updates

Chapter 9 (Circulatory, I00-I99): 42 new codes
Chapter 11 (Digestive, K00-K95): 27 new codes, 1 revision, 3 invalidated
Chapter 19 (Injury/Poisoning, S00-T88): 30 new codes, 3 invalidated
Chapter 21 (Factors, Z00-Z99): 25 new codes, 1 revision, 2 invalidated
Chapter 12 (Skin, L00-L99): 8 new codes, 3 invalidated
Chapter 10 (Respiratory, J00-J99): 7 new codes
Chapter 6 (Nervous System, G00-G99): 7 new codes, 1 revision, 1 invalidated

ICD-10-CM Coding Guidelines Updates

The 2025 ICD-10-CM Official Guidelines updates are minimal, primarily focusing on harmonization with new code introductions.

Status Code Updates

Category Z17 title expanded to: Estrogen, and other hormones and factors receptor status

Z17 - Estrogen, and other hormones and factors receptor status
Z18 - Retained foreign body fragments
Z19 - Hormone sensitivity malignancy status

New Guideline: Presymptomatic Type 1 Diabetes

Guideline I.C.4.a.1.(a): Codes E10.A- (Type 1 diabetes mellitus, presymptomatic) are assigned for early-stage type 1 diabetes that predates the onset of diabetic symptoms. Note: The age of a patient is not the sole determining factor, though most type 1 diabetics develop the condition before reaching puberty.

Significant Updates by Chapter

Chapter 2: Neoplasms

Codes in categories C81-C84 now have options to report "in remission." Categories C86 and C88 now have options for "not having achieved remission" or "in remission."

Chapter 4: Endocrine, Nutritional and Metabolic

Three new subcategories of codes have been added:

E10.A-: Type 1 diabetes mellitus, presymptomatic
E16.A-: Hypoglycemia level
E66.8: Obesity class

Several subcategories have new instructional notes directing reporting of additional codes for injectable non-insulin antidiabetic drugs (Z79.85) and/or hypoglycemia level codes.

Chapter 5: Mental and Behavioral Disorders

Eating disorder codes in category F50 (anorexia, bulimia, binge eating) have been expanded to specify severity. New codes specifically report PICA and rumination disorder in adults.

Chapter 11: Digestive System

Codes in category K60 (fissure and fistula of anal and rectal regions) have been expanded to specify complexity and nature of occurrence.

Chapter 13: Musculoskeletal System

Lumbar and lumbosacral intervertebral disc degeneration codes (M51.36 and M51.37) expanded to specify type of pain:

Discogenic back pain only
Lower extremity pain only
Discogenic back pain and lower extremity pain
Without mention of lumbar back pain or lower extremity pain

Chapter 19: Injury and Poisoning

Category T45 receives 6 new codes for poisoning by, adverse effect of, and underdosing of immune checkpoint inhibitors and immunostimulant drugs. Code T81.32 expanded with four new codes for greater specificity in reporting disruption of internal surgical wounds.

Chapter 21: Factors Influencing Health Status

Category Z17 updated with 8 new codes to indicate positive/negative receptor status and combined receptor status. New subcategory Z67.A- added for Duffy phenotype.